Agricoltura, What is Mad Cow Disease?
agricoltura | info | prezzo | dati | produzione
Mad Cow Disease - What to Know - as part of the education series by GeoBeats.
Mad Cow Disease - What is It?
Scientifically named Bovine Spongiform Encephalopathy, it is a progressive neurological disease that affects a cow's nervous system. Once infected, the cow's behavior becomes erratic - inability to walk, uncontrolled movements and lower milk production. Incubation period can be months, even years. There's no known treatment and the disease is fatal.
How Do Cows Get Infected?
A cow gets infected with the disease if they eat diseased feed which has abnormal proteins called prions found in brains, spinal cords, and other parts. These prions cause the degeneration in brain, giving it a spongy like appearance.
How Can It Affect Us?
Humans don't get mad cow disease as such but they get a variant of it if they eat the diseased cattle tissue. Health officials in the US and elsewhere control such scenarios by periodic sampling and prohibiting cattle parts in feed which may contain prions.
Where Has It Been Reported So Far?
Although United Kingdom has been most impacted by the mad cow disease so far, the BSE has been reported in many countries around the word. Millions of cattle have been slaughtered and nearly 200,000 cows have died. Around 200 humans have lost their lives.
In the US recently, a cow tested positive for the disease but the health officials say that the infected cow wasn't designated for meat consumption and it was an atypical strain of the disease.
Commento
-
Its called like pieron not P-rion
-
So a cow gets infected by eating infected cattle or whatever? Then how did the infected cattle that the now infected cow get infected?
-
i didnt even think BSE was relevant anymore... i was a child living in the UK when the UK had a massive epidemic of it ! no one ate beef for months ! and we started seeing things like horse and kangeroo meat in the stores instead
-
The fact that all prions are 100% fatal and have no cure or treatment scares the living hell out of me. That's why I stopped eating beef completely. It can take up to decades before a person finds out they have a degenerative prion caused disease like "CJD" or "Creutzfeldt–Jakob Disease" which is what the disease "Mad Cow" or "BSE" or "Bovine Spongiform Encephalopathy" causes in humans. If you think "ALS" or "Amyotrophic Lateral Sclerosis" is scary then you'd find "CJD" horrifying. Some scientists believe "ALS" may be caused by a prion that's yet to be discovered. That would make a lot of sense as "ALS" has many similar symptoms to other prion diseases like "CJD". If you find this stuff interesting than I suggest looking up, on YouTube (there's a great documentary), the prion disease called "Kuru" which was spread through the Fore tribe in Papua New Guinea via cannibalism. Honestly, I suggest any infectious disease documentary (bacteria, virus, parasite, fungus, prion).
-
Should we give the cows quassia Cayenne (French Guiana). this plant produces quinine, and off reduces the activity of the prion
-
O.05: Transmission of prions to primates after extended silent incubation periods: Implications for BSE and scrapie risk assessment in human populations
Emmanuel Comoy, Jacqueline Mikol, Val erie Durand, Sophie Luccantoni, Evelyne Correia, Nathalie Lescoutra, Capucine Dehen, and Jean-Philippe Deslys Atomic Energy Commission; Fontenay-aux-Roses, France
Prion diseases (PD) are the unique neurodegenerative proteinopathies reputed to be transmissible under field conditions since decades. The transmission of Bovine Spongiform Encephalopathy (BSE) to humans evidenced that an animal PD might be zoonotic under appropriate conditions. Contrarily, in the absence of obvious (epidemiological or experimental) elements supporting a transmission or genetic predispositions, PD, like the other proteinopathies, are reputed to occur spontaneously (atpical animal prion strains, sporadic CJD summing 80% of human prion cases). Non-human primate models provided the first evidences supporting the transmissibiity of human prion strains and the zoonotic potential of BSE. Among them, cynomolgus macaques brought major information for BSE risk assessment for human health (Chen, 2014), according to their phylogenetic proximity to humans and extended lifetime. We used this model to assess the zoonotic potential of other animal PD from bovine, ovine and cervid origins even after very long silent incubation periods. We recently observed the direct transmission of a natural classical scrapie isolate to macaque after a 10-year silent incubation period, with features similar to some reported for human cases of sporadic CJD, albeit requiring fourfold longe incubation than BSE. Scrapie, as recently evoked in humanized mice (Cassard, 2014), is the third potentially zoonotic PD (with BSE and L-type BSE), ***thus questioning the origin of human sporadic cases. We will present an updated panorama of our different transmission studies and discuss the implications of such extended incubation periods on risk assessment of animal PD for human health.
===============
***thus questioning the origin of human sporadic cases...TSS
===============
https://prion2015.files.wordpress.com/2015/05/prion2015abstracts.pdf
Saturday, May 30, 2015
PRION 2015 ORAL AND POSTER CONGRESSIONAL ABSTRACTS
http://transmissiblespongiformencephalopathy.blogspot.com/2015/05/prion-2015-oral-and-poster.html
LATE-BREAKING ABSTRACTS
O18
Zoonotic Potential of CWD Prions
Liuting Qing1, Ignazio Cali1,2, Jue Yuan1, Shenghai Huang3, Diane Kofskey1, Pierluigi Gambetti1, Wenquan Zou1, Qingzhong Kong1 1Case Western Reserve University, Cleveland, Ohio, USA, 2Second University of Naples, Naples, Italy, 3Encore Health Resources, Houston, Texas, USA
Chronic wasting disease (CWD) is a widespread and expanding prion disease in free-ranging and captive cervid species in North America. The zoonotic potential of CWD prions is a serious public health concern. Current literature generated with in vitro methods and in vivo animal models (transgenic mice, macaques and squirrel monkeys) reports conflicting results. The susceptibility of human CNS and peripheral organs to CWD prions remains largely unresolved. In our earlier bioassay experiments using several humanized transgenic mouse lines, we detected protease-resistant PrPSc in the spleen of two out of 140 mice that were intracerebrally inoculated with natural CWD isolates, but PrPSc was not detected in the brain of the same mice. Secondary passages with such PrPSc-positive CWD-inoculated humanized mouse spleen tissues led to efficient prion transmission with clear clinical and pathological signs in both humanized and cervidized transgenic mice. Furthermore, a recent bioassay with natural CWD isolates in a new humanized transgenic mouse line led to clinical prion infection in 2 out of 20 mice. These results indicate that the CWD prion has the potential to infect human CNS and peripheral lymphoid tissues and that there might be asymptomatic human carriers of CWD infection.
==================
**These results indicate that the CWD prion has the potential to infect human CNS and peripheral lymphoid tissues and that there might be asymptomatic human carriers of CWD infection.**
==================
https://prion2015.files.wordpress.com/2015/05/programguide1.pdf
I strenuously once again urge the FDA and its industry constituents, to make it MANDATORY that all ruminant feed be banned to all ruminants, and this should include all cervids as soon as possible for the following reasons...
======
In the USA, under the Food and Drug Administrations BSE Feed Regulation (21 CFR 589.2000) most material (exceptions include milk, tallow, and gelatin) from deer and elk is prohibited for use in feed for ruminant animals. With regards to feed for non-ruminant animals, under FDA law, CWD positive deer may not be used for any animal feed or feed ingredients. For elk and deer considered at high risk for CWD, the FDA recommends that these animals do not enter the animal feed system.
***However, this recommendation is guidance and not a requirement by law.
======
31 Jan 2015 at 20:14 GMT
* Ruminant feed ban for cervids in the United States? *
31 Jan 2015 at 20:14 GMT
http://www.plosone.org/annotation/listThread.action?root=85351
Tuesday, June 23, 2015
Report on the monitoring and testing of ruminants for the presence of transmissible spongiform encephalopathies (TSEs) in the EU in 2013 Final version 18 May 2015
http://transmissiblespongiformencephalopathy.blogspot.com/2015/06/report-on-monitoring-and-testing-of.html
Sunday, July 12, 2015
Insights into CWD and BSE species barriers using real-time conversion
http://transmissiblespongiformencephalopathy.blogspot.com/2015/07/insights-into-cwd-and-bse-species.html
-
What sense does it make to feed cows with cows? I get that it's cheaper for the rancher, but seriously?
-
prion disease is awful and scary
-
Anyone get brought here by ssundee?
-
Thanks.....now im vegetarian :(
-
This sounds like mAd snail disease 😁😹
-
MOOOO
-
I learned that can turn you into a zombie
-
This was perfect! Just what I needed to learn in less than 5 minutes :D 👌
-
1:17 Dat ass doe... xD
-
One time this chick from a cow farm came into my cooking class and fed us a bunch of bs about how all the cows are happy sitting in their shit pens and if they have mad cow disease it won't affect us, and she gave us a bunch of propaganda, etc... My teacher let her do this presentation because she gave us free meat.
-
Mcdonalds...
-
sounds like rabies
-
It was also on the news, if I recall correctly. Like one of those "possible e. coli contamination safety recall".
-
Because Costco issued a recall or whatever it's called. They called anyone who bought the berries (Costco probably keeps track of what you buy, idk) and told those possibly infected to go get checked or treated for it and they'd cover it. Gotta love Costco.
Mad Cow Disease - What to Know - as part of the education series by GeoBeats. Mad Cow Disease - What is It? Scientifically named Bovine Spongiform Encephalopathy, it is a progressive neurological disease that affects a cow's nervous system. Once infected, the cow's behavior becomes erratic - inability to walk, uncontrolled movements and lower milk production. Incubation period can be months, even years. There's no known treatment and the disease is fatal. How Do Cows Get Infected? A cow gets infected with the disease if they eat diseased feed which has abnormal proteins called prions found in brains, spinal cords, and other parts. These prions cause the degeneration in brain, giving it a spongy like appearance. How Can It Affect Us? Humans don't get mad cow disease as such but they get a variant of it if they eat the diseased cattle tissue. Health officials in the US and elsewhere control such scenarios by periodic sampling and prohibiting cattle parts in feed which may contain prions. Where Has It Been Reported So Far? Although United Kingdom has been most impacted by the mad cow disease so far, the BSE has been reported in many countries around the word. Millions of cattle have been slaughtered and nearly 200,000 cows have died. Around 200 humans have lost their lives. In the US recently, a cow tested positive for the disease but the health officials say that the infected cow wasn't designated for meat consumption and it was an atypical strain of the disease.
Commento
Emmanuel Comoy, Jacqueline Mikol, Val erie Durand, Sophie Luccantoni, Evelyne Correia, Nathalie Lescoutra, Capucine Dehen, and Jean-Philippe Deslys Atomic Energy Commission; Fontenay-aux-Roses, France
Prion diseases (PD) are the unique neurodegenerative proteinopathies reputed to be transmissible under field conditions since decades. The transmission of Bovine Spongiform Encephalopathy (BSE) to humans evidenced that an animal PD might be zoonotic under appropriate conditions. Contrarily, in the absence of obvious (epidemiological or experimental) elements supporting a transmission or genetic predispositions, PD, like the other proteinopathies, are reputed to occur spontaneously (atpical animal prion strains, sporadic CJD summing 80% of human prion cases). Non-human primate models provided the first evidences supporting the transmissibiity of human prion strains and the zoonotic potential of BSE. Among them, cynomolgus macaques brought major information for BSE risk assessment for human health (Chen, 2014), according to their phylogenetic proximity to humans and extended lifetime. We used this model to assess the zoonotic potential of other animal PD from bovine, ovine and cervid origins even after very long silent incubation periods. We recently observed the direct transmission of a natural classical scrapie isolate to macaque after a 10-year silent incubation period, with features similar to some reported for human cases of sporadic CJD, albeit requiring fourfold longe incubation than BSE. Scrapie, as recently evoked in humanized mice (Cassard, 2014), is the third potentially zoonotic PD (with BSE and L-type BSE), ***thus questioning the origin of human sporadic cases. We will present an updated panorama of our different transmission studies and discuss the implications of such extended incubation periods on risk assessment of animal PD for human health.
===============
***thus questioning the origin of human sporadic cases...TSS
===============
https://prion2015.files.wordpress.com/2015/05/prion2015abstracts.pdf
Saturday, May 30, 2015
PRION 2015 ORAL AND POSTER CONGRESSIONAL ABSTRACTS
http://transmissiblespongiformencephalopathy.blogspot.com/2015/05/prion-2015-oral-and-poster.html
LATE-BREAKING ABSTRACTS
O18
Zoonotic Potential of CWD Prions
Liuting Qing1, Ignazio Cali1,2, Jue Yuan1, Shenghai Huang3, Diane Kofskey1, Pierluigi Gambetti1, Wenquan Zou1, Qingzhong Kong1 1Case Western Reserve University, Cleveland, Ohio, USA, 2Second University of Naples, Naples, Italy, 3Encore Health Resources, Houston, Texas, USA
Chronic wasting disease (CWD) is a widespread and expanding prion disease in free-ranging and captive cervid species in North America. The zoonotic potential of CWD prions is a serious public health concern. Current literature generated with in vitro methods and in vivo animal models (transgenic mice, macaques and squirrel monkeys) reports conflicting results. The susceptibility of human CNS and peripheral organs to CWD prions remains largely unresolved. In our earlier bioassay experiments using several humanized transgenic mouse lines, we detected protease-resistant PrPSc in the spleen of two out of 140 mice that were intracerebrally inoculated with natural CWD isolates, but PrPSc was not detected in the brain of the same mice. Secondary passages with such PrPSc-positive CWD-inoculated humanized mouse spleen tissues led to efficient prion transmission with clear clinical and pathological signs in both humanized and cervidized transgenic mice. Furthermore, a recent bioassay with natural CWD isolates in a new humanized transgenic mouse line led to clinical prion infection in 2 out of 20 mice. These results indicate that the CWD prion has the potential to infect human CNS and peripheral lymphoid tissues and that there might be asymptomatic human carriers of CWD infection.
==================
**These results indicate that the CWD prion has the potential to infect human CNS and peripheral lymphoid tissues and that there might be asymptomatic human carriers of CWD infection.**
==================
https://prion2015.files.wordpress.com/2015/05/programguide1.pdf
I strenuously once again urge the FDA and its industry constituents, to make it MANDATORY that all ruminant feed be banned to all ruminants, and this should include all cervids as soon as possible for the following reasons...
======
In the USA, under the Food and Drug Administrations BSE Feed Regulation (21 CFR 589.2000) most material (exceptions include milk, tallow, and gelatin) from deer and elk is prohibited for use in feed for ruminant animals. With regards to feed for non-ruminant animals, under FDA law, CWD positive deer may not be used for any animal feed or feed ingredients. For elk and deer considered at high risk for CWD, the FDA recommends that these animals do not enter the animal feed system.
***However, this recommendation is guidance and not a requirement by law.
======
31 Jan 2015 at 20:14 GMT
* Ruminant feed ban for cervids in the United States? *
31 Jan 2015 at 20:14 GMT
http://www.plosone.org/annotation/listThread.action?root=85351
Tuesday, June 23, 2015
Report on the monitoring and testing of ruminants for the presence of transmissible spongiform encephalopathies (TSEs) in the EU in 2013 Final version 18 May 2015
http://transmissiblespongiformencephalopathy.blogspot.com/2015/06/report-on-monitoring-and-testing-of.html
Sunday, July 12, 2015
Insights into CWD and BSE species barriers using real-time conversion
http://transmissiblespongiformencephalopathy.blogspot.com/2015/07/insights-into-cwd-and-bse-species.html